HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: TET2 (Q6N021)
Methylcytosine dioxygenase TET2 (EC 1.14.11.80)
Gene: TET2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.50	0.593

Property	Details
Experiments	35271311, 36931259, 23353889
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 2002
+	Hs
		909681 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		982143 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		683446 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		927169 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		647002 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		684120 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		909832 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06
+	Hs
		904887 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06
+	Hs
		982300 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06
+	Hs
		647124 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06