HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: LCA5 (Q86VQ0)
Lebercilin (Leber congenital amaurosis 5 protein)
Gene: LCA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.50	0.619

Property	Details
Experiments	26638075, 33961781, unassigned1272, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 697
+	Hs
		909762 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		LCA5_HUMAN (1-697): 1.31e-79: 269: 100.00
+	Hs
		982225 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		LCA5_HUMAN (1-697): 1.31e-79: 269: 100.00
+	Hs
		683509 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		LCA5_HUMAN (1-697): 1.31e-79: 269: 100.00
+	Hs
		909658 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MRCKA_HUMAN (33-529): 5.45e-46: 179: 15.41
+	Hs
		904690 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MRCKA_HUMAN (33-529): 5.45e-46: 179: 15.41
+	Hs
		982116 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		MRCKA_HUMAN (33-529): 5.45e-46: 179: 15.41
+	Hs
		683425 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		MRCKA_HUMAN (33-529): 5.45e-46: 179: 15.41
+	Hs
		551656 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DESP_HUMAN (31-635): 8.92e-16: 83.9: 12.21
+	Mm
		93548 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		DESP_MOUSE (47-591): 8.24e-13: 74.3: 13.01
+	Hs
		551677 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		DESP_HUMAN (31-635): 8.92e-16: 83.9: 12.21
+	Hs
		909846 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RBCC1_HUMAN (123-533): 3.58e-10: 65.8: 16.55
+	Hs
		909524 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ROCK1_HUMAN (11-508): 8.34e-10: 64.3: 10.62
+	Hs
		725130 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYH10_HUMAN (231-628): 2.38e-09: 63.1: 6.48
+	Hs
		728460 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYH11_HUMAN (274-635): 7.97e-09: 61.2: 11.17
+	Hs
		904900 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RBCC1_HUMAN (123-533): 3.58e-10: 65.8: 16.55
+	Hs
		725128 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MYH10_HUMAN (231-628): 2.38e-09: 63.1: 6.48
+	Hs
		982137 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		MRCKG_HUMAN (80-478): 2.56e-10: 66.1: 13.40
+	Hs
		982312 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		RBCC1_HUMAN (123-533): 3.58e-10: 65.8: 16.55
+	Hs
		728471 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		MYH11_HUMAN (274-635): 7.97e-09: 61.2: 11.17
+	Hs
		683564 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		RBCC1_HUMAN (123-533): 3.58e-10: 65.8: 16.55