HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: MYLK2 (Q9H1R3)
Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)
Gene: MYLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 596
+	Hs
		910017 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYLK2_HUMAN (1-596): 0: 528: 100.00
+	At
		965291 14332_ARATH (4-244): 1.39e-141: 398: 61.32		CDPK1_ARATH (128-580): 4.38e-140: 421: 25.33
+	Hs
		909621 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYLK3_HUMAN (10-588): 3.51e-137: 420: 42.81
+	At
		802001 14334_ARATH (4-244): 5e-140: 395: 60.91		CDPK1_ARATH (128-580): 4.38e-140: 421: 25.33
+	At
		788694 14335_ARATH (3-244): 5.67e-136: 385: 59.02		CDPK1_ARATH (128-580): 4.38e-140: 421: 25.33
+	Hs
		681770 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AKT1_HUMAN (172-588): 3.1e-135: 404: 21.43
+	Hs
		910174 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KCC2A_HUMAN (271-596): 2.76e-134: 402: 32.33
+	Hs
		909532 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KCC2D_HUMAN (280-596): 5.43e-133: 399: 30.53
+	Hs
		681766 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AKT1_HUMAN (172-588): 3.1e-135: 404: 21.43
+	Hs
		904532 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KCC2D_HUMAN (280-596): 5.43e-133: 399: 30.53
+	Hs
		683826 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		KCC2A_HUMAN (271-596): 2.76e-134: 402: 32.33
+	Hs
		681776 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		AKT1_HUMAN (172-588): 3.1e-135: 404: 21.43
+	Mm
		515221 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		KCC2A_MOUSE (271-581): 3.42e-134: 402: 32.38
+	Mm
		926819 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		KCC2D_MOUSE (280-596): 5.43e-133: 399: 30.53
+	Hs
		910132 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DAPK2_HUMAN (289-584): 5.32e-71: 234: 39.67
+	Hs
		200101 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DAPK3_HUMAN (271-566): 4.44e-67: 227: 40.06
+	Hs
		200099 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DAPK3_HUMAN (271-566): 4.44e-67: 227: 40.06
+	Hs
		200105 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		DAPK3_HUMAN (271-566): 4.44e-67: 227: 40.06
+	Hs
		200089 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		DAPK3_HUMAN (271-566): 4.44e-67: 227: 40.06
+	Hs
		927352 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		TITIN_HUMAN (289-591): 2.8e-56: 207: 35.97