HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: DACT1 (Q9NYF0)
Dapper homolog 1 (hDPR1) (Dapper antagonist of catenin 1) (Hepatocellular carcinoma novel gene 3 protein)
Gene: DACT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21262972
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005080 - protein kinase C binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 836
+	Hs
		910089 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DACT1_HUMAN (1-836): 0: 773: 100.00
+	Hs
		982550 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		DACT1_HUMAN (1-836): 0: 773: 100.00
+	Hs
		683759 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		DACT1_HUMAN (1-836): 0: 773: 100.00
+	Hs
		927586 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		DACT1_HUMAN (1-836): 0: 773: 100.00
+	Hs
		647324 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		DACT1_HUMAN (1-836): 0: 773: 100.00
+	Hs
		684356 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		DACT1_HUMAN (1-836): 0: 773: 100.00
+	Hs
		297821 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		K0754_HUMAN (167-637): 1.15e-27: 123: 12.16
+	Hs
		909712 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		OTOG_HUMAN (158-602): 3.41e-14: 79.4: 12.21
+	Hs
		904746 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		OTOG_HUMAN (158-602): 3.41e-14: 79.4: 12.21
+	Hs
		982175 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		OTOG_HUMAN (158-602): 3.41e-14: 79.4: 12.21
+	Hs
		203217 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SYNJ1_HUMAN (99-632): 2.1e-09: 63.6: 14.50
+	Hs
		203222 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		SYNJ1_HUMAN (99-632): 2.1e-09: 63.6: 14.50
+	Hs
		297815 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		K0754_HUMAN (167-637): 1.15e-27: 123: 12.16
+	Hs
		297824 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		K0754_HUMAN (167-637): 1.15e-27: 123: 12.16
+	Hs
		683472 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		OTOG_HUMAN (158-602): 3.41e-14: 79.4: 12.21
+	Hs
		927196 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		OTOG_HUMAN (158-602): 3.41e-14: 79.4: 12.21
+	Hs
		647025 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		OTOG_HUMAN (158-602): 3.41e-14: 79.4: 12.21