Interactor 1: CNTF (P51642)
Ciliary neurotrophic factor (CNTF)
Gene: CNTF
Interactor 2: IL6RB (Q00560)
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
Gene: Il6st
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15051883 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CNTF~fn3, CNTF~IL6Ra-bind |
| Common GO terms | GO:0005127 - ciliary neurotrophic factor receptor binding GO:0005138 - interleukin-6 receptor binding GO:0008284 - positive regulation of cell population proliferation GO:0043524 - negative regulation of neuron apoptotic process GO:0097696 - cell surface receptor signaling pathway via STAT |
| Homologous interactions | 5 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
