HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.50	0.565

Property	Details
Experiments	28065597, 35384245
Identification Methods	two hybrid, affinity chromatography technology, ubiquitin reconstruction
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 1374
+	Hs
		905979 PP1A_HUMAN (1-326): 0: 576: 88.79		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		737881 PP1G_HUMAN (1-327): 0: 569: 86.89		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		906524 PP1B_HUMAN (1-327): 0: 597: 100.00		LMTK2_HUMAN (9-1366): 0: 690: 29.74
+	Hs
		906008 PP1A_HUMAN (1-326): 0: 576: 88.79		LMTK2_HUMAN (9-1366): 0: 690: 29.74
+	Hs
		737908 PP1G_HUMAN (1-327): 0: 569: 86.89		LMTK2_HUMAN (9-1366): 0: 690: 29.74
+	Hs
		906090 PP1A_HUMAN (1-326): 0: 576: 88.79		LMTK3_HUMAN (7-1342): 9.67e-159: 518: 29.10
+	Hs
		384600 PP1B_HUMAN (1-327): 0: 597: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384599 PP1A_HUMAN (1-326): 0: 576: 88.79		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384627 PP2AA_HUMAN (8-303): 2.77e-176: 491: 45.79		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77