HitPredict

Interactor 1: DHX57 (Q6P158)
Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57)
Gene: DHX57

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1386 Hs			1 334
+	Hs
		1278246 DHX29_HUMAN (231-1386): 0: 940: 32.11		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1062576 DHX9_HUMAN (269-1383): 0: 894: 29.56		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1370369 DHX36_HUMAN (395-1386): 0: 863: 37.98		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		207608 DHX15_HUMAN (492-1331): 0: 785: 24.70		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		187995 DHX29_HUMAN (231-1386): 0: 940: 32.11		EIF3H_HUMAN (52-320): 2.18e-66: 214: 18.57
+	Hs
		138084 DHX9_HUMAN (269-1383): 0: 894: 29.56		PSDE_HUMAN (50-331): 1.68e-79: 246: 31.51
+	Hs
		906508 DHX9_HUMAN (269-1383): 0: 894: 29.56		PSMD7_HUMAN (52-325): 1.07e-66: 214: 14.79
+	Hs
		131408 DHX9_HUMAN (269-1383): 0: 894: 29.56		EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48
+	Hs
		1271474 DHX30_HUMAN (473-1361): 0: 709: 30.91		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		137867 DHX15_HUMAN (492-1331): 0: 785: 24.70		PSDE_HUMAN (50-331): 1.68e-79: 246: 31.51
+	Sc
		1046072 DHR1_YEAST (417-1320): 0: 681: 22.58		RPN8_YEAST (53-326): 4.47e-57: 190: 16.61
+	Hs
		1218563 DHX40_HUMAN (542-1378): 0: 706: 22.49		MYSM1_HUMAN (39-172): 3.52e-29: 119: 23.29
+	Hs
		1370377 YTDC2_HUMAN (513-741): 5.49e-59: 226: 51.87		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00