HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	15016827
Identification Methods	far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Metallophos~PDZ, Metallophos~PDZ_5, PDZ~STPPase_N, PDZ_5~STPPase_N
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 327 Hs			1 1098
+	Rn
		193533 PP1B_RAT (1-327): 0: 597: 100.00		NEB1_RAT (1-1093): 2.67e-113: 379: 90.04
+	Hs
		906197 PP1A_HUMAN (1-326): 0: 576: 88.79		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		738120 PP1G_HUMAN (1-327): 0: 569: 86.89		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Rn
		193534 PP1G_RAT (1-327): 0: 569: 86.89		NEB1_RAT (1-1093): 2.67e-113: 379: 90.04
+	Hs
		906059 PP1A_HUMAN (1-326): 0: 576: 88.79		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Mm
		926531 PP1G_MOUSE (1-327): 0: 569: 86.89		DLG3_MOUSE (311-1098): 3.85e-70: 253: 13.06
+	Hs
		737775 PP1G_HUMAN (1-327): 0: 569: 86.89		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Mm
		906652 PP1B_MOUSE (1-327): 0: 597: 100.00		DLG4_MOUSE (376-1098): 3.11e-50: 192: 13.00
+	Hs
		905921 PP1A_HUMAN (1-326): 0: 576: 88.79		DLG2_HUMAN (116-922): 4.42e-55: 209: 12.95
+	Rn
		192520 PP1B_RAT (1-327): 0: 597: 100.00		NEB2_RAT (1-826): 2.53e-45: 178: 43.42
+	Mm
		906274 PP1A_MOUSE (1-326): 0: 576: 88.49		DLG4_MOUSE (376-1098): 3.11e-50: 192: 13.00
+	Mm
		906654 PP1B_MOUSE (1-327): 0: 597: 100.00		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		906570 PP1B_HUMAN (1-327): 0: 597: 100.00		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Rn
		192519 PP1A_RAT (1-326): 0: 576: 88.79		NEB2_RAT (1-826): 2.53e-45: 178: 43.42
+	Rn
		192521 PP1G_RAT (1-327): 0: 569: 86.89		NEB2_RAT (1-826): 2.53e-45: 178: 43.42
+	Mm
		906288 PP1A_MOUSE (1-326): 0: 576: 88.49		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		906098 PP1A_HUMAN (1-326): 0: 576: 88.79		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Mm
		926545 PP1G_MOUSE (1-327): 0: 569: 86.89		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		737997 PP1G_HUMAN (1-327): 0: 569: 86.89		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Hs
		528366 PP1A_HUMAN (1-326): 0: 576: 88.79		MYH6_HUMAN (574-1090): 1.43e-15: 84.4: 11.28