HitPredict

Interactor 1: PRS4 (P62191)
26S proteasome regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)
Gene: PSMC1

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	26496610, 26186194, 28514442, 33961781, 34761751, 19615732, 18922472, 19490896
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 329
+	Hs
		906852 PRS4_HUMAN (1-440): 8.84e-140: 409: 100.00		Q5LJA5_HUMAN (1-329): 3.25e-170: 478: 92.14
+	Hs
		913378 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		907203 PRS8_HUMAN (55-433): 1.06e-123: 366: 46.70		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		798791 PRS6B_HUMAN (50-433): 1.06e-122: 364: 48.96		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Sp
		736971 PRS4_SCHPO (7-435): 5.88e-125: 371: 72.85		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Sp
		252277 PRS6B_SCHPO (65-422): 1.07e-117: 350: 49.58		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Hs
		906888 PRS4_HUMAN (1-440): 8.84e-140: 409: 100.00		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		913326 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		907110 PRS8_HUMAN (55-433): 1.06e-123: 366: 46.70		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		798725 PRS6B_HUMAN (50-433): 1.06e-122: 364: 48.96		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29