HitPredict

Interactor 1: AAK1 (Q2M2I8)
AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)
Gene: AAK1

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 961 Hs			1 1121
+	Hs
		1153405 BMP2K_HUMAN (37-767): 7.31e-125: 409: 47.28		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Mm
		93677 TNIK_MOUSE (24-782): 6.51e-116: 388: 13.73		E9Q6H8_MOUSE (11-1107): 6.02e-111: 377: 29.55
+	Mm
		949327 TNIK_MOUSE (24-782): 6.51e-116: 388: 13.73		Q6ZPK1_MOUSE (62-1107): 4.91e-89: 314: 28.04
+	Hs
		1183127 MARK2_HUMAN (6-739): 5.77e-127: 405: 15.61		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		876427 MARK2_HUMAN (6-739): 5.77e-127: 405: 15.61		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Mm
		1194491 MINK1_MOUSE (23-896): 8.63e-120: 398: 15.18		CNKR2_MOUSE (119-516): 8.05e-46: 181: 17.87
+	Hs
		1336112 TNIK_HUMAN (24-770): 5.75e-117: 391: 15.27		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		876440 MINK1_HUMAN (23-889): 2.9e-117: 391: 15.13		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		1263851 TNIK_HUMAN (24-770): 5.75e-117: 391: 15.27		CNKR2_HUMAN (119-516): 1.33e-45: 181: 17.65
+	Mm
		949351 TNIK_MOUSE (24-782): 6.51e-116: 388: 13.73		CNKR2_MOUSE (119-516): 8.05e-46: 181: 17.87
+	Hs
		1331402 BMP2K_HUMAN (37-767): 7.31e-125: 409: 47.28		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1183121 MARK2_HUMAN (6-739): 5.77e-127: 405: 15.61		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1233543 MINK1_HUMAN (23-889): 2.9e-117: 391: 15.13		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1331590 TNIK_HUMAN (24-770): 5.75e-117: 391: 15.27		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1183099 MARK2_HUMAN (6-739): 5.77e-127: 405: 15.61		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Mm
		93268 TNIK_MOUSE (24-782): 6.51e-116: 388: 13.73		E9PXB7_MOUSE (59-486): 2.89e-28: 125: 13.02
+	Hs
		1233533 MINK1_HUMAN (23-889): 2.9e-117: 391: 15.13		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Hs
		808172 MARK2_HUMAN (6-739): 5.77e-127: 405: 15.61		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17
+	Hs
		808315 TNIK_HUMAN (24-770): 5.75e-117: 391: 15.27		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17
+	Mm
		808345 TNIK_MOUSE (24-782): 6.51e-116: 388: 13.73		NEDD4_MOUSE (14-322): 7.06e-14: 78.5: 11.64