HitPredict

Interactor 1: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Interactor 2: NR1I3 (Q14994)
Nuclear receptor subfamily 1 group I member 3 (Constitutive activator of retinoid response) (Constitutive active response) (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67)
Gene: NR1I3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15604093, 8603043
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 406 Hs			1 352
+	Hs
		587150 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RXRA_HUMAN (8-351): 9.29e-108: 324: 23.99
+	Hs
		265859 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		NR1I2_HUMAN (8-351): 3.57e-105: 317: 40.55
+	Hs
		509930 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		VDR_HUMAN (8-351): 4.64e-105: 316: 33.74
+	Hs
		500362 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RARB_HUMAN (9-351): 9.51e-99: 301: 27.25
+	Hs
		906980 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		ERR3_HUMAN (2-351): 1.1e-96: 296: 24.15
+	Hs
		907027 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		HNF4G_HUMAN (10-351): 3.41e-97: 295: 24.71
+	Hs
		369311 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		ESR1_HUMAN (2-351): 1.82e-94: 294: 21.66
+	Hs
		487934 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RARA_HUMAN (9-351): 2.99e-95: 292: 28.12
+	Rn
		411261 PRS8_RAT (1-406): 1.42e-136: 398: 100.00		ESR1_RAT (1-351): 7.08e-93: 290: 22.13
+	Hs
		530791 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RARG_HUMAN (9-351): 8.22e-94: 288: 26.09
+	Hs
		907008 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		NR1H3_HUMAN (8-351): 1.28e-92: 285: 29.61
+	Hs
		611412 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		NR4A1_HUMAN (2-351): 1.9e-90: 284: 23.86
+	Hs
		369310 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		ESR1_HUMAN (2-351): 1.82e-94: 294: 21.66
+	Hs
		500475 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		THB_HUMAN (1-351): 2.09e-89: 277: 29.00
+	Hs
		907111 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		ESR2_HUMAN (2-352): 4.23e-88: 276: 21.76
+	Hs
		510012 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		ERR1_HUMAN (4-351): 2.72e-88: 273: 24.65
+	Hs
		798664 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		NR1I3_HUMAN (1-352): 1.93e-102: 307: 100.00
+	Hs
		611411 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		NR4A1_HUMAN (2-351): 1.9e-90: 284: 23.86
+	Hs
		906889 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		ESR2_HUMAN (2-352): 4.23e-88: 276: 21.76
+	Hs
		369145 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		ESR1_HUMAN (2-351): 1.82e-94: 294: 21.66