Protein: SH23A
SH2 domain-containing protein 3A (Novel SH2-containing protein 1)

Gene: SH23A, SH2D3A
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q9BRG2

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0007254 - JNK cascade
GO:0007264 - small GTPase-mediated signal transduction
GO:0033138 - positive regulation of peptidyl-serine phosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

338911

EGFR
Epidermal growth factor receptor

4

20

Small-scale

0.900

High

882528

BCAR1
Breast cancer anti-estrogen resistance protein 1

3

20

Small-scale

0.757

High

310885

RASL1
RasGAP-activating-like protein 1

1

20

High-throughput

0.618

High

383953

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.579

High

601989

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.579

High

905051

1433G
14-3-3 protein gamma

2

20

High-throughput

0.549

High

647230

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

422565

CENPB
Major centromere autoantigen B

2

1

High-throughput

0.526

High

1035400

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.489

High

153028

IMPA2
Inositol monophosphatase 2

1

1

High-throughput

0.489

High

175348

LX15B
Polyunsaturated fatty acid lipoxygenase ALOX15B

1

6

High-throughput

0.489

High

198467

KLK10
Kallikrein-10

1

3

High-throughput

0.489

High

241709

F262
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

1

4

High-throughput

0.489

High

245836

CATL2
Cathepsin L2

1

3

High-throughput

0.489

High

259879

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

9

High-throughput

0.489

High

344331

AACT
Alpha-1-antichymotrypsin

1

8

High-throughput

0.489

High

396409

APOD
Apolipoprotein D

1

5

High-throughput

0.489

High

396795

S10A8
Protein S100-A8

1

11

High-throughput

0.489

High

416505

S10A9
Protein S100-A9

1

14

High-throughput

0.489

High

420723

HEXA
Beta-hexosaminidase subunit alpha

1

4

High-throughput

0.489

High

427114

CATD
Cathepsin D

1

1

High-throughput

0.489

High

428624

INVO
Involucrin

1

17

High-throughput

0.489

High

453985

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

3

High-throughput

0.489

High

504662

HSP7C
Heat shock cognate 71 kDa protein

1

20

High-throughput

0.489

High

530959

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

2

High-throughput

0.489

High

533988

ANXA8
Annexin A8

1

11

High-throughput

0.489

High

546635

ARSA
Arylsulfatase A

1

4

High-throughput

0.489

High

567241

CXA1
Gap junction alpha-1 protein

1

11

High-throughput

0.489

High

596312

FILA
Filaggrin

1

11

High-throughput

0.489

High

596348

ASPG
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase

1

1

High-throughput

0.489

High

611325

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

3

High-throughput

0.489

High

629173

ZA2G
Zinc-alpha-2-glycoprotein

1

5

High-throughput

0.489

High

639060

S100P
Protein S100-P

1

14

High-throughput

0.489

High

668020

SPB3
Serpin B3

1

9

High-throughput

0.489

High

678499

S10A7
Protein S100-A7

1

14

High-throughput

0.489

High

683672

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.489

High

820374

SPB4
Serpin B4

1

9

High-throughput

0.489

High

909966

1433E
14-3-3 protein epsilon

1

9

High-throughput

0.489

High

927466

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.489

High

945725

NGAL
Neutrophil gelatinase-associated lipocalin

1

6

High-throughput

0.489

High

949093

HTRA3
Serine protease HTRA3

1

1

High-throughput

0.489

High

1048373

SCRB2
Lysosome membrane protein 2

1

6

High-throughput

0.489

High

1079056

CYTM
Cystatin-M

1

1

High-throughput

0.489

High

1083771

ECM1
Extracellular matrix protein 1

1

1

High-throughput

0.489

High

1125343

FILA2
Filaggrin-2

1

12

High-throughput

0.489

High

1134405

KPRP
Keratinocyte proline-rich protein

1

3

High-throughput

0.489

High

1151752

P20D1
N-fatty-acyl-amino acid synthase/hydrolase PM20D1

1

1

High-throughput

0.489

High

1173096

FBX50
F-box only protein 50

1

2

High-throughput

0.489

High

1175137

TBA1A
Tubulin alpha-1A chain

1

20

High-throughput

0.489

High

1243646

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

1

High-throughput

0.489

High

1261803

POF1B
Protein POF1B

1

2

High-throughput

0.489

High

1296795

CPNS2
Calpain small subunit 2

1

3

High-throughput

0.489

High

1309995

RNAS7
Ribonuclease 7

1

1

High-throughput

0.489

High

1309999

CBPA4
Carboxypeptidase A4

1

1

High-throughput

0.489

High

684296

1433S
14-3-3 protein sigma

1

20

High-throughput

0.470

High

72336

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

3

High-throughput

0.437

High

1306568

TS101
Tumor susceptibility gene 101 protein

1

3

High-throughput

0.417

High

66431

A2ML1
Alpha-2-macroglobulin-like protein 1

1

3

High-throughput

0.407

High

124334

RFXAP
Regulatory factor X-associated protein

1

0

High-throughput

0.279

Low

271836

CREG1
Protein CREG1

1

0

High-throughput

0.279

Low

277273

TUSC2
Tumor suppressor candidate 2

1

0

High-throughput

0.279

Low

396279

ARGI1
Arginase-1

1

0

High-throughput

0.279

Low

437693

BGLR
Beta-glucuronidase

1

0

High-throughput

0.279

Low

546881

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.279

Low

572142

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.279

Low

588445

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

648073

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.279

Low

1037487

ASAH1
Acid ceramidase

1

0

High-throughput

0.279

Low

1159699

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.279

Low

1184886

GDPD3
Lysophospholipase D GDPD3

1

0

High-throughput

0.279

Low

1300229

GSDMA
Gasdermin-A

1

0

High-throughput

0.279

Low

1309996

RISC
Retinoid-inducible serine carboxypeptidase

1

0

High-throughput

0.279

Low

1309998

PCYOX
Prenylcysteine oxidase 1

1

0

High-throughput

0.279

Low

1309997

NXF1
Nuclear RNA export factor 1

1

0

Small-scale

0.261

Low


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Last updated: 15 Jul 2024