HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	U-box~UQ_con, UQ_con~WD40
Common GO terms	GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 504
+	Hs
		895955 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		849435 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		TBL1R_HUMAN (134-466): 1.2e-76: 251: 14.57
+	Hs
		1282344 UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00		TBL1R_HUMAN (134-466): 1.2e-76: 251: 14.57
+	Hs
		908940 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		196986 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84
+	Hs
		903084 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48