HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	35271311, 36931259, 17979178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1128
+	Hs
		909667 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		910023 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		883468 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		909789 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		161349 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Hs
		910111 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DAPLE_HUMAN (33-349): 6.45e-16: 85.6: 16.36