HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: ARHGG (Q5VV41)
Rho guanine nucleotide exchange factor 16 (Ephexin-4)
Gene: ARHGEF16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 709
+	Hs
		909489 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG5_HUMAN (21-706): 2.23e-107: 359: 27.87
+	Hs
		909781 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHGJ_HUMAN (18-708): 1.68e-104: 338: 26.71
+	Hs
		909921 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SPT13_HUMAN (68-628): 2.4e-101: 326: 16.58
+	Hs
		910068 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG4_HUMAN (35-649): 2.82e-99: 321: 16.07
+	Hs
		909717 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		FGD6_HUMAN (38-671): 5.47e-93: 318: 14.99
+	Hs
		909883 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG2_HUMAN (59-702): 1.75e-93: 313: 14.99
+	Hs
		909551 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG7_HUMAN (59-686): 2.22e-94: 311: 13.06
+	Hs
		909491 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		AKP13_HUMAN (82-702): 2.13e-89: 308: 13.27
+	Mm
		910228 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		ARG28_MOUSE (42-669): 6.4e-88: 304: 13.91
+	Hs
		909803 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARG28_HUMAN (42-669): 1.3e-87: 303: 14.85
+	Hs
		297126 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PKHG5_HUMAN (276-571): 5.33e-12: 71.6: 25.60
+	Sp
		788722 RAD24_SCHPO (2-255): 7.25e-135: 382: 70.77		RGF1_SCHPO (278-542): 1.46e-17: 89.7: 25.83