Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE
Interactor 2: M3K3 (Q99759)
Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)
Gene: MAP3K3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 0.60 | 0.747 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9452471, 35271311, 36931259, 36736316, 14743216, 16407301, 12392720 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000165 - MAPK cascade GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0035556 - intracellular signal transduction |
| Homologous interactions | 15 |
Homologous interactions
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Last updated: 15 Jul 2024
