HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: KLC2 (Q9H0B6)
Kinesin light chain 2 (KLC 2)
Gene: KLC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	35271311, 36931259, 17979178
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0045296 - cadherin binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 622
+	Hs
		910078 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KLC4_HUMAN (7-618): 1.11e-105: 334: 69.13
+	Mm
		910337 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		KLC4_MOUSE (7-618): 1.34e-101: 323: 67.69
+	Hs
		174775 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		OGT1_HUMAN (58-526): 3.14e-51: 192: 16.63
+	Mm
		910304 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		OGT1_MOUSE (58-526): 2.65e-51: 192: 16.63
+	At
		788447 14331_ARATH (4-245): 3.88e-144: 405: 75.41		SEC_ARATH (4-455): 2.1e-38: 154: 16.15
+	Hs
		909889 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		TTC28_HUMAN (203-568): 1.33e-20: 99: 11.03
+	Hs
		909688 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		909475 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50