HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0016020 - membrane GO:0045296 - cadherin binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 7388
+	Mm
		93548 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		DESP_MOUSE (2737-3805): 1.11e-27: 127: 8.89
+	Hs
		909464 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		297821 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		K0754_HUMAN (757-1741): 1.73e-10: 70.9: 10.05
+	Hs
		909544 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39