HitPredict

Interactor 1: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000165 - MAPK cascade GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0044877 - protein-containing complex binding GO:0097110 - scaffold protein binding and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 255 Mm			1 1730
+	Hs
		909986 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SHAN3_HUMAN (1-1730): 0: 601: 95.21
+	Hs
		910023 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21
+	Hs
		883468 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21
+	Hs
		909455 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ANK2_HUMAN (212-349): 7.67e-29: 129: 24.64