HitPredict

Interactor 1: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Interactor 2: TAOK2 (Q6ZQ29)
Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2)
Gene: TAOK2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000165 - MAPK cascade GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030424 - axon GO:0098978 - glutamatergic synapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 255 Mm			1 1240
+	Xl
		223344 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q804T2_XENLA (3-700): 1.25e-155: 485: 16.12
+	Hs
		647862 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK3_HUMAN (2-700): 1.3e-152: 478: 15.37
+	Hs
		909524 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ROCK1_HUMAN (25-889): 5.36e-145: 475: 17.01
+	Mm
		910231 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK3_MOUSE (2-700): 2.05e-151: 475: 15.65
+	Mm
		910234 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK2_MOUSE (5-700): 5.69e-146: 461: 15.18
+	Hs
		909730 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK2_HUMAN (5-700): 1.36e-142: 453: 15.20
+	Xl
		223345 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q8QGV3_XENLA (3-700): 2.71e-140: 447: 14.53
+	Hs
		910106 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK1_HUMAN (2-700): 5.38e-133: 428: 15.83
+	Mm
		910318 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK1_MOUSE (14-700): 1.65e-131: 424: 16.20
+	Dm
		90534 1433E_DROME (1-254): 2.95e-146: 411: 82.69		E1JGN0_DROME (2-700): 5.39e-133: 437: 13.09
+	Mm
		910308 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK4_MOUSE (14-666): 7.7e-128: 413: 18.02
+	Hs
		910013 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SIK2_HUMAN (28-783): 9.25e-124: 407: 15.80
+	Hs
		909502 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		STK4_HUMAN (24-425): 1.21e-117: 376: 34.38
+	Hs
		909512 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		STK3_HUMAN (15-444): 2.6e-115: 370: 31.66
+	At
		965360 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CIPKC_ARATH (27-489): 1.39e-119: 381: 19.03
+	At
		788672 14333_ARATH (1-253): 3.45e-147: 413: 74.12		CIPKC_ARATH (27-489): 1.39e-119: 381: 19.03
+	At
		1280891 14337_ARATH (2-255): 7.73e-147: 412: 71.21		CIPKC_ARATH (27-489): 1.39e-119: 381: 19.03
+	Sc
		439641 BMH2_YEAST (4-242): 1.14e-134: 382: 77.08		SPS1_YEAST (24-359): 2.66e-52: 194: 36.44
+	Sc
		439634 BMH1_YEAST (2-243): 2.43e-134: 381: 75.72		SPS1_YEAST (24-359): 2.66e-52: 194: 36.44