HitPredict

Interactor 1: ARF6 (P62330)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arf~PH
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 175 Hs			1 1121
+	Hs
		913121 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		574754 ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		125370 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		876346 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		950545 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		CYH2_HUMAN (105-300): 1.31e-44: 168: 21.50
+	Hs
		913064 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		CYH2_HUMAN (105-300): 1.31e-44: 168: 21.50
+	Rn
		913236 ARF6_RAT (1-175): 2.17e-65: 199: 100.00		CYH2_RAT (105-300): 1.44e-44: 168: 21.50
+	Hs
		574749 ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		912917 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		CYH1_HUMAN (105-281): 4.55e-43: 164: 21.69
+	Hs
		950560 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		950712 ARF5_HUMAN (2-173): 4.69e-69: 209: 65.12		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Mm
		913234 ARF6_MOUSE (1-175): 2.17e-65: 199: 100.00		CYH1_MOUSE (105-281): 6.84e-43: 163: 21.69
+	Hs
		918949 RAB1A_HUMAN (1-174): 6.74e-67: 204: 18.99		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1328144 RAB1B_HUMAN (10-174): 1.3e-66: 203: 19.41		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		913111 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		897405 ARF3_HUMAN (2-175): 4.91e-65: 198: 69.54		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		574767 ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91
+	Hs
		950569 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91
+	Hs
		574746 ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74		WWP1_HUMAN (42-252): 1.75e-13: 77.4: 17.05
+	Hs
		950704 ARF5_HUMAN (2-173): 4.69e-69: 209: 65.12		WWP1_HUMAN (42-252): 1.75e-13: 77.4: 17.05