HitPredict

Interactor 1: ARF6 (P62330)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Interactor 2: RFIP4 (Q86YS3)
Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4) (Arfophilin-2)
Gene: RAB11FIP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	16148947, 17030804
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome GO:0030139 - endocytic vesicle GO:0030496 - midbody GO:0032154 - cleavage furrow GO:0032456 - endocytic recycling and 1 others more... GO:0055038 - recycling endosome membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 175 Hs			1 637
+	Hs
		950648 ARF5_HUMAN (2-173): 4.69e-69: 209: 65.12		RFIP4_HUMAN (1-637): 1.15e-56: 204: 100.00
+	Hs
		256696 ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74		RFIP3_HUMAN (20-636): 5.64e-30: 128: 23.67
+	Hs
		256701 ARF5_HUMAN (2-173): 4.69e-69: 209: 65.12		RFIP3_HUMAN (20-636): 5.64e-30: 128: 23.67
+	Hs
		256699 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		RFIP3_HUMAN (20-636): 5.64e-30: 128: 23.67
+	Hs
		912880 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		LIPA1_HUMAN (237-624): 1.2e-25: 115: 16.83
+	Hs
		254465 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		ROCK2_HUMAN (235-625): 8.05e-13: 73.8: 13.04