HitPredict

Interactor 1: ARF6 (P62330)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Interactor 2: US6NL (Q92738)
USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre)
Gene: USP6NL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 175 Hs			1 828
+	Dm
		778397 ARF6_DROME (1-174): 4e-68: 206: 97.13		Q8IPP5_DROME (4-715): 7.58e-132: 428: 17.95
+	Dm
		778412 ARF6_DROME (1-174): 4e-68: 206: 97.13		Q9VNG9_DROME (4-715): 1.43e-131: 427: 17.95
+	Hs
		715075 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		UBP6_HUMAN (1-554): 2.62e-120: 397: 30.45
+	Hs
		913085 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		TB10A_HUMAN (27-503): 9.92e-102: 326: 24.07
+	Hs
		912934 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		913204 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		RBGP1_HUMAN (59-586): 1.36e-90: 310: 19.46