HitPredict

Interactor 1: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20618440
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 245
+	Mm
		935546 ACTBL_MOUSE (4-377): 0: 721: 89.04		1433F_MOUSE (2-240): 1.16e-107: 312: 74.07
+	Zm
		73744 B4F989_MAIZE (1-377): 0: 621: 87.53		K7U5A5_MAIZE (3-239): 5.22e-139: 392: 62.86
+	Mm
		926767 ACTG_MOUSE (4-377): 0: 598: 94.39		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Mm
		926769 ACTS_MOUSE (1-377): 0: 598: 97.88		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Hs
		891673 ACTB_HUMAN (4-377): 0: 598: 94.12		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		926908 ACTG_HUMAN (4-377): 0: 598: 94.39		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		926910 ACTC_HUMAN (1-377): 0: 598: 98.41		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		891665 ACTB_HUMAN (4-377): 0: 598: 94.12		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		909433 ACTC_HUMAN (1-377): 0: 598: 98.41		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		646763 ACTB_HUMAN (4-377): 0: 598: 94.12		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		646783 ACTG_HUMAN (4-377): 0: 598: 94.39		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	At
		862527 ACT7_ARATH (1-377): 0: 591: 88.06		14332_ARATH (3-239): 6.89e-143: 401: 65.15
+	Hs
		646777 ACTA_HUMAN (1-377): 0: 596: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		683256 ACTC_HUMAN (1-377): 0: 598: 98.41		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		904433 ACTC_HUMAN (1-377): 0: 598: 98.41		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		683952 ACTG_HUMAN (4-377): 0: 598: 94.39		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97
+	Hs
		683954 ACTS_HUMAN (1-377): 0: 598: 97.88		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97
+	Hs
		683941 ACTA_HUMAN (1-377): 0: 596: 100.00		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97