HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: DOCK7 (Q96N67)
Dedicator of cytokinesis protein 7
Gene: DOCK7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DHR-2_Lobe_B~Ras, DHR-2_Lobe_C~Ras
Common GO terms	GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 2140
+	Hs
		925526 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK7_HUMAN (1-2140): 0: 2782: 100.00
+	Hs
		925448 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK8_HUMAN (2-2139): 0: 2478: 55.69
+	Hs
		925518 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK6_HUMAN (2-2140): 0: 2420: 64.50
+	At
		1105136 RAC4_ARATH (1-179): 5.45e-87: 255: 49.16		SPK1_ARATH (99-885): 0: 618: 19.54
+	At
		1248269 RAC9_ARATH (6-196): 6.09e-77: 231: 45.60		SPK1_ARATH (99-885): 0: 618: 19.54
+	Dm
		776892 RAC1_DROME (1-196): 1.58e-77: 231: 53.06		Q8MQW7_DROME (1552-2131): 3.47e-140: 475: 16.80
+	Mm
		925807 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		DOCK1_MOUSE (303-859): 7.11e-122: 430: 18.99
+	Hs
		925276 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK1_HUMAN (303-859): 4.62e-120: 424: 18.64
+	Hs
		915674 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DOCK1_HUMAN (303-859): 4.62e-120: 424: 18.64
+	Hs
		545372 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		DOCK1_HUMAN (303-859): 4.62e-120: 424: 18.64
+	Hs
		925620 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK5_HUMAN (303-859): 3.61e-76: 284: 15.15
+	Hs
		925486 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK2_HUMAN (300-875): 1.99e-70: 265: 16.20
+	Hs
		545535 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		DOCK2_HUMAN (300-875): 1.99e-70: 265: 16.20
+	Hs
		925429 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK4_HUMAN (342-862): 8.54e-68: 257: 17.93
+	Hs
		925425 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK3_HUMAN (348-862): 5.42e-50: 198: 17.41
+	Hs
		925588 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK9_HUMAN (2-279): 3.87e-49: 196: 22.41
+	Hs
		915942 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DOCK9_HUMAN (2-279): 3.87e-49: 196: 22.41
+	Hs
		925332 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOC11_HUMAN (1-212): 1.49e-44: 180: 26.75
+	Hs
		915729 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DOC11_HUMAN (1-212): 1.49e-44: 180: 26.75
+	Hs
		545421 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		DOC11_HUMAN (1-212): 1.49e-44: 180: 26.75