HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: TB10A (Q9BXI6)
TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein) (Rab27A-GAP-alpha)
Gene: TBC1D10A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 508
+	Hs
		925323 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		TB10B_HUMAN (5-465): 8.33e-128: 393: 59.44
+	Hs
		915717 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		TB10B_HUMAN (5-465): 8.33e-128: 393: 59.44
+	Hs
		892404 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		TB10B_HUMAN (5-465): 8.33e-128: 393: 59.44
+	Hs
		564554 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		TB10B_HUMAN (5-465): 8.33e-128: 393: 59.44
+	Hs
		925494 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		900761 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		915879 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		545541 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		951204 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		892524 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		894279 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		715076 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		UBP6_HUMAN (13-462): 1.93e-92: 309: 21.03
+	Hs
		715074 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		UBP6_HUMAN (13-462): 1.93e-92: 309: 21.03
+	Hs
		925738 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		TBD2B_HUMAN (11-380): 1.37e-81: 274: 24.39
+	Hs
		232655 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		TBCD4_HUMAN (13-459): 2.02e-83: 283: 21.01
+	Hs
		916079 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		TBD2B_HUMAN (11-380): 1.37e-81: 274: 24.39
+	Hs
		951462 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		TBD2B_HUMAN (11-380): 1.37e-81: 274: 24.39
+	Hs
		894392 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		TBD2A_HUMAN (12-375): 6.06e-82: 275: 26.79
+	Hs
		892684 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		TBD2B_HUMAN (11-380): 1.37e-81: 274: 24.39
+	Hs
		321279 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		TBCD8_HUMAN (100-312): 1.41e-29: 125: 35.35