HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: TAOK3 (Q9H2K8)
Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)
Gene: TAOK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 898
+	Hs
		925606 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		TAOK3_HUMAN (1-898): 0: 644: 100.00
+	Hs
		296408 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		STK10_HUMAN (5-897): 1.77e-143: 451: 22.06
+	Hs
		647868 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MARK3_HUMAN (2-651): 3.07e-145: 450: 16.31
+	Hs
		296406 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		STK10_HUMAN (5-897): 1.77e-143: 451: 22.06
+	Hs
		159189 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CSKP_HUMAN (20-855): 3.57e-141: 444: 15.29
+	Hs
		925766 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MRCKB_HUMAN (6-865): 6.99e-134: 441: 14.62
+	Hs
		159188 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CSKP_HUMAN (20-855): 3.57e-141: 444: 15.29
+	Rn
		92842 RHOA_RAT (1-196): 3.27e-78: 233: 83.16		CTRO_RAT (10-844): 3.18e-128: 428: 17.78
+	Hs
		925253 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ROCK1_HUMAN (10-898): 6.6e-130: 424: 16.98
+	Hs
		925384 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MARK2_HUMAN (2-651): 7.99e-131: 413: 15.63
+	Mm
		925809 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		PAK2_MOUSE (2-299): 1.06e-106: 341: 36.48
+	Hs
		925245 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PAK2_HUMAN (19-299): 2.42e-106: 340: 37.76
+	Hs
		925763 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		M4K5_HUMAN (12-295): 3.02e-53: 201: 38.91
+	Dm
		1177643 Q7JWS8_DROME (1-196): 8.76e-78: 232: 51.78		PAK_DROME (19-298): 2.12e-52: 197: 40.91
+	Mm
		103566 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		G5E884_MOUSE (19-298): 1.41e-51: 191: 41.61
+	Hs
		277602 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PAK3_HUMAN (19-298): 2.06e-51: 191: 41.61
+	Hs
		925244 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PAK1_HUMAN (19-298): 1.43e-51: 191: 41.61
+	Hs
		925344 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MRCKA_HUMAN (582-898): 9.62e-12: 71.4: 17.43
+	Hs
		254468 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ROCK2_HUMAN (278-896): 1.29e-11: 71: 13.36
+	Hs
		254467 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ROCK2_HUMAN (278-896): 1.29e-11: 71: 13.36