Protein: TRX
Histone-lysine N-methyltransferase trithorax (EC 2.1.1.355) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Lysine N-methyltransferase 2A)

Gene: TRX
Organism: Drosophila melanogaster
Interactions: 35
UniProt ID: P20659

Gene Ontology (top 5):
GO:0000123 - histone acetyltransferase complex
GO:0001654 - eye development
GO:0003682 - chromatin binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

381690

H3
Histone H3

5

20

Small-scale

0.911

High

633968

TRX
Histone-lysine N-methyltransferase trithorax

3

18

Small-scale

0.872

High

633989

ASH1
Histone-lysine N-methyltransferase ash1

2

18

Small-scale

0.775

High

121972

M9PH39
histone acetyltransferase

2

20

Small-scale

0.754

High

633979

ASH2
Set1/Ash2 histone methyltransferase complex subunit ASH2

2

20

Small-scale

0.754

High

402256

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

12

Small-scale

0.618

High

633969

PC
Polycomb group protein Pc

1

20

Small-scale

0.618

High

633982

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

7

Small-scale

0.595

High

559020

PP12
Serine/threonine-protein phosphatase alpha-2 isoform

2

5

High-throughput

0.560

High

633975

Q24090
GH08712p

2

4

Small-scale

0.552

High

633981

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

11

Small-scale

0.552

High

633971

PP11
Serine/threonine-protein phosphatase alpha-1 isoform

1

5

High-throughput

0.508

High

633972

PP1B
Serine/threonine-protein phosphatase beta isoform

1

5

High-throughput

0.508

High

633974

PP13
Serine/threonine-protein phosphatase alpha-3 isoform

1

5

High-throughput

0.508

High

144547

O01368
histone acetyltransferase

1

20

High-throughput

0.492

High

633986

Q9VG38
Suppressor of fused homolog

1

1

High-throughput

0.481

High

633973

MNB
Serine/threonine-protein kinase minibrain

1

14

Small-scale

0.479

High

633983

SPT5H
Transcription elongation factor SPT5

1

17

Small-scale

0.479

High

633984

ASX
Polycomb group protein Asx

1

18

Small-scale

0.479

High

633985

NUP98
Nuclear pore complex protein Nup98-Nup96

1

12

Small-scale

0.479

High

633977

Q27279
Suppressor of fused homolog

1

1

High-throughput

0.457

High

2432

NOVA
RNA-binding protein Pasilla

1

13

High-throughput

0.445

High

613909

SGG
Protein kinase shaggy

1

3

High-throughput

0.445

High

633976

NETB
Netrin-B

1

3

High-throughput

0.442

High

633990

Q9W0L7
ubiquitinyl hydrolase 1

1

4

High-throughput

0.442

High

56195

A1ZA03
Pms2

1

1

High-throughput

0.439

High

391872

HSP83
Heat shock protein 83

1

13

Small-scale

0.437

High

633978

Q8IPU8
BNIP3, isoform B

1

0

High-throughput

0.426

High

303850

O76417
MutL homolog PMS2

1

1

High-throughput

0.417

High

633970

FAT
Cadherin-related tumor suppressor

1

1

Small-scale

0.417

High

118772

M9NFI9
Neurabin-1

1

5

High-throughput

0.407

High

633980

NRX4
Neurexin-4

1

3

High-throughput

0.407

High

633987

Q9VGH9
SET domain binding factor, isoform A

1

3

High-throughput

0.381

High

633988

Q9VR87
AT16570p

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025