HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: VANG2 (Q9ULK5)
Vang-like protein 2 (Loop-tail protein 1 homolog) (Strabismus 1) (Van Gogh-like protein 2)
Gene: VANGL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 521
+	Hs
		925451 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		900711 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		915849 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		545509 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		436415 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		951170 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		892496 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		894231 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		564619 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		120550 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		925726 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		901044 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		545698 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		436571 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		951456 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		892679 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		894582 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		564736 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		120711 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		VANG2_HUMAN (1-521): 0: 725: 100.00