HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 2229
+	Hs
		1127616 H2B2F_HUMAN (1-126): 2.21e-54: 168: 98.41		PRC2B_HUMAN (1-2229): 0: 619: 100.00
+	Hs
		241550 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		PRC2B_HUMAN (1-2229): 0: 619: 100.00
+	Hs
		1087196 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		NIPBL_HUMAN (85-1137): 1.88e-36: 154: 11.37
+	Hs
		918442 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		NIPBL_HUMAN (85-1137): 1.88e-36: 154: 11.37
+	Hs
		918773 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		1129830 H2B2F_HUMAN (1-126): 2.21e-54: 168: 98.41		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		617962 H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		1087299 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		1264778 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		241595 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		918561 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		918628 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		MINT_HUMAN (296-2220): 2.45e-17: 91.8: 8.49
+	Hs
		241615 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		1056847 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56
+	Hs
		1056919 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56
+	Hs
		918364 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56
+	Hs
		241475 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		820873 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		820935 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		821000 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24