HitPredict

Interactor 1: RAB3C (P62823)
Ras-related protein Rab-3C
Gene: RAB3C

Interactor 2: RIMS2 (Q9EQZ7)
Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 2)
Gene: RIMS2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12578829
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras, PDZ~Ras
Common GO terms	GO:0017157 - regulation of exocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 227 Mm			1 1530
+	Mm
		722693 RAB3D_MOUSE (9-227): 4.64e-90: 266: 75.34		RIMS2_MOUSE (1-1530): 0: 896: 100.00
+	Rn
		919028 RAB3C_RAT (1-227): 6.33e-95: 278: 100.00		RIMS2_RAT (1-1530): 0: 719: 74.36
+	Rn
		926103 RAB3A_RAT (9-227): 2.43e-88: 261: 82.73		RIMS2_RAT (1-1530): 0: 719: 74.36
+	Ce
		1094851 RAB3_CAEEL (9-227): 6.47e-89: 262: 73.52		RIM_CAEEL (26-1519): 1.14e-134: 457: 22.18
+	Mm
		919021 RAB3C_MOUSE (1-227): 6.33e-95: 278: 100.00		RIMS1_MOUSE (24-1530): 3.2e-91: 328: 33.01
+	Mm
		722691 RAB3D_MOUSE (9-227): 4.64e-90: 266: 75.34		RIMS1_MOUSE (24-1530): 3.2e-91: 328: 33.01
+	Mm
		926089 RAB3A_MOUSE (9-227): 2.43e-88: 261: 82.73		RIMS1_MOUSE (24-1530): 3.2e-91: 328: 33.01
+	Hs
		1134943 RAB1B_HUMAN (23-227): 8.8e-90: 264: 41.95		SYT6_HUMAN (1158-1510): 1.61e-43: 169: 18.47
+	Mm
		812771 RAB3C_MOUSE (1-227): 6.33e-95: 278: 100.00		RP3A_MOUSE (577-1056): 3.89e-31: 133: 12.02
+	Mm
		722679 RAB3D_MOUSE (9-227): 4.64e-90: 266: 75.34		RP3A_MOUSE (577-1056): 3.89e-31: 133: 12.02
+	Mm
		812772 RAB3A_MOUSE (9-227): 2.43e-88: 261: 82.73		RP3A_MOUSE (577-1056): 3.89e-31: 133: 12.02
+	Rn
		812780 RAB3A_RAT (9-227): 2.43e-88: 261: 82.73		RP3A_RAT (577-1056): 7.68e-31: 133: 12.35
+	Hs
		591501 RAB3A_HUMAN (9-227): 3.93e-88: 261: 82.73		RP3A_HUMAN (569-1056): 9.12e-31: 132: 13.24
+	Hs
		48320 RB11A_HUMAN (20-227): 4.3e-99: 288: 35.85		ESYT2_HUMAN (821-1328): 1.24e-19: 97.8: 14.91
+	Hs
		914240 RB11A_HUMAN (20-227): 4.3e-99: 288: 35.85		SYTL5_HUMAN (93-379): 3.86e-13: 76.7: 13.76
+	Hs
		914318 RB11A_HUMAN (20-227): 4.3e-99: 288: 35.85		ESYT1_HUMAN (816-939): 5.03e-10: 66.6: 32.54
+	Hs
		914274 RB11A_HUMAN (20-227): 4.3e-99: 288: 35.85		SYTL4_HUMAN (828-933): 3.93e-09: 63.5: 34.91
+	Hs
		591478 RAB3A_HUMAN (9-227): 3.93e-88: 261: 82.73		RIMS1_HUMAN (956-1505): 7.04e-15: 82.8: 12.07
+	Hs
		591482 RAB3A_HUMAN (9-227): 3.93e-88: 261: 82.73		SYTL5_HUMAN (93-379): 3.86e-13: 76.7: 13.76
+	Hs
		591484 RAB3A_HUMAN (9-227): 3.93e-88: 261: 82.73		SYTL4_HUMAN (828-933): 3.93e-09: 63.5: 34.91