HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: TRI33 (Q9UPN9)
E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)
Gene: TRIM33

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	29643511
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 1127
+	Hs
		1318738 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM2_HUMAN (115-491): 4.9e-86: 296: 20.74
+	Hs
		1356055 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM1_HUMAN (98-496): 3.35e-71: 254: 17.21
+	Hs
		175730 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI18_HUMAN (117-493): 1.15e-70: 251: 17.65
+	Hs
		175664 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI18_HUMAN (117-493): 1.15e-70: 251: 17.65
+	Hs
		1151762 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		Q6GX22_HUMAN (117-496): 1.33e-68: 246: 17.03
+	Hs
		1333889 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI45_HUMAN (124-462): 3.99e-65: 233: 25.70
+	Ce
		715104 UBC2_CAEEL (1-147): 1e-82: 241: 93.88		NHL1_CAEEL (102-914): 4.94e-63: 234: 14.69
+	Hs
		919763 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI46_HUMAN (112-482): 1.72e-59: 221: 17.84
+	Hs
		734819 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI23_HUMAN (91-479): 1.27e-59: 217: 16.20
+	Hs
		734581 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI23_HUMAN (91-479): 1.27e-59: 217: 16.20
+	Mm
		895980 UB2D1_MOUSE (1-147): 7.06e-83: 241: 89.12		LIN41_MOUSE (97-522): 1.17e-56: 214: 18.67
+	Hs
		262201 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM3_HUMAN (179-629): 2.88e-56: 211: 16.02
+	Hs
		262167 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRIM3_HUMAN (179-629): 2.88e-56: 211: 16.02
+	Hs
		1318719 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM5_HUMAN (168-541): 1.28e-55: 203: 12.47
+	Hs
		584923 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		RO52_HUMAN (178-518): 2.8e-54: 199: 13.91
+	Hs
		1318358 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM8_HUMAN (120-642): 2.09e-52: 195: 14.95
+	Hs
		1336390 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI39_HUMAN (172-439): 1.14e-52: 195: 14.71
+	Hs
		919850 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRIM8_HUMAN (120-642): 2.09e-52: 195: 14.95
+	Hs
		919810 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI63_HUMAN (163-461): 2.08e-53: 192: 14.42
+	Hs
		919720 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TIF1B_HUMAN (631-1105): 6.36e-25: 114: 18.20