HitPredict

Interactor 1: UB2D2 (P62838)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2)
Gene: Ube2d2

Interactor 2: TRI17 (Q7TPM3)
E3 ubiquitin-protein ligase TRIM17 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM17) (Tripartite motif-containing protein 17)
Gene: Trim17

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	22976837
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0051865 - protein autoubiquitination GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Mm			1 477
+	Hs
		584923 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		RO52_HUMAN (1-477): 1.39e-152: 444: 36.21
+	Hs
		1336390 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI39_HUMAN (7-476): 8.32e-145: 426: 33.47
+	Hs
		1377469 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI17_HUMAN (1-477): 1.14e-144: 424: 76.52
+	Hs
		919822 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI11_HUMAN (1-477): 2.55e-142: 418: 43.63
+	Hs
		537142 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI27_HUMAN (1-472): 1.76e-137: 407: 33.07
+	Hs
		536779 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI27_HUMAN (1-472): 1.76e-137: 407: 33.07
+	Hs
		135045 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI38_HUMAN (1-470): 2.49e-128: 382: 32.35
+	Hs
		135019 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI38_HUMAN (1-470): 2.49e-128: 382: 32.35
+	Hs
		919852 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRIM7_HUMAN (11-463): 1.55e-123: 371: 32.44
+	Hs
		1318719 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM5_HUMAN (1-470): 5.75e-118: 356: 27.29
+	Hs
		1204911 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI50_HUMAN (1-471): 1.95e-117: 355: 24.85
+	Hs
		1354526 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI10_HUMAN (1-464): 9.24e-117: 353: 28.10
+	Hs
		919773 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI50_HUMAN (1-471): 1.95e-117: 355: 24.85
+	Hs
		1313765 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI62_HUMAN (6-470): 2.39e-113: 344: 25.26
+	Hs
		919841 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI62_HUMAN (6-470): 2.39e-113: 344: 25.26
+	Hs
		1285831 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI43_HUMAN (1-459): 4.88e-110: 334: 29.74
+	Hs
		919816 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI43_HUMAN (1-459): 4.88e-110: 334: 29.74
+	Hs
		919846 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI34_HUMAN (1-470): 1.34e-102: 317: 29.03
+	Hs
		1357712 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI35_HUMAN (3-476): 1.82e-99: 309: 25.45
+	Hs
		919800 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI41_HUMAN (1-44): 9.4e-12: 69.4: 58.33