HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Hs			1 543
+	Hs
		921697 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		1202777 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		826605 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826604 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821157 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		821156 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573205 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		573204 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		826748 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Sc
		579432 GBB_YEAST (2-340): 1.33e-76: 243: 36.53		TCPH_YEAST (2-542): 0: 587: 62.45
+	Sc
		579430 GBB_YEAST (2-340): 1.33e-76: 243: 36.53		TCPE_YEAST (2-526): 0: 568: 29.98
+	Hs
		573346 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Sc
		579422 GBB_YEAST (2-340): 1.33e-76: 243: 36.53		TCPG_YEAST (2-527): 0: 546: 30.68
+	Hs
		821355 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		821152 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573412 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		573201 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843145 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843144 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843273 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79