HitPredict

Interactor 1: GBB1 (P62874)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: Gnb1

Interactor 2: RACK1 (P68040)
Small ribosomal subunit protein RACK1 (12-3) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) (Receptor of activated protein kinase C 1) (p205) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene: RACK1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12359736
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0044297 - cell body
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 340 Mm			1 317
+	Hs
		921518 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		920934 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		929610 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		903109 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Sc
		630844 NLE1_YEAST (2-297): 8.98e-80: 253: 18.55		NLE1_YEAST (59-316): 3.4e-70: 228: 20.92
+	Hs
		903349 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70
+	Hs
		903428 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70
+	Dm
		1358845 WDS_DROME (3-215): 1.22e-57: 192: 19.55		WDS_DROME (3-223): 1.09e-62: 204: 25.78
+	Hs
		903077 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70
+	Hs
		560870 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GBB3_HUMAN (15-260): 4.33e-11: 64.7: 27.38
+	Hs
		560857 GBB3_HUMAN (1-340): 1.83e-104: 311: 83.24		GBB3_HUMAN (15-260): 4.33e-11: 64.7: 27.38
+	Hs
		792949 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43
+	Hs
		903551 NLE1_HUMAN (3-124): 6.68e-32: 126: 25.41		WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70
+	At
		824875 GBB_ARATH (132-340): 5.38e-39: 143: 23.32		GPLPC_ARATH (100-317): 1.01e-49: 169: 23.81
+	At
		188993 GBB_ARATH (132-340): 5.38e-39: 143: 23.32		GBLPA_ARATH (100-317): 3.63e-49: 168: 26.41
+	At
		824860 GBB_ARATH (132-340): 5.38e-39: 143: 23.32		GPLPB_ARATH (100-317): 1.72e-49: 168: 24.35
+	Dm
		1358859 WDS_DROME (3-215): 1.22e-57: 192: 19.55		FBXW7_DROME (3-128): 9.64e-20: 92: 19.53
+	Hs
		903418 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		FBXW7_HUMAN (3-128): 4.32e-21: 95.4: 24.63