HitPredict

Interactor 1: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Interactor 2: TCPW (Q92526)
T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (CCT-zeta-like) (Chaperonin containing T-complex polypeptide 1 subunit 6B) (TCP-1-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303)
Gene: CCT6B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Hs			1 530
+	Hs
		921697 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		TCPH_HUMAN (2-529): 0: 568: 27.43
+	Hs
		770778 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		TCPZ_HUMAN (1-530): 0: 558: 85.85
+	Hs
		921038 GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29		TCPH_HUMAN (2-529): 0: 568: 27.43
+	Hs
		826605 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		TCPG_HUMAN (3-527): 0: 551: 28.20
+	Hs
		770777 GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29		TCPZ_HUMAN (1-530): 0: 558: 85.85
+	Hs
		821157 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		TCPE_HUMAN (3-527): 0: 541: 30.34
+	Hs
		826604 GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29		TCPG_HUMAN (3-527): 0: 551: 28.20
+	Hs
		821156 GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29		TCPE_HUMAN (3-527): 0: 541: 30.34
+	Hs
		921021 GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29		TCPW_HUMAN (1-530): 0: 540: 100.00
+	Hs
		1202777 WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39		TCPH_HUMAN (2-529): 0: 568: 27.43
+	Hs
		770916 WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39		TCPZ_HUMAN (1-530): 0: 558: 85.85
+	Hs
		826748 WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39		TCPG_HUMAN (3-527): 0: 551: 28.20
+	Sc
		579424 GBB_YEAST (2-340): 5.29e-76: 241: 36.01		TCPZ_YEAST (3-530): 0: 555: 54.53
+	Hs
		1202774 WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39		TCPW_HUMAN (1-530): 0: 540: 100.00
+	Sc
		579432 GBB_YEAST (2-340): 5.29e-76: 241: 36.01		TCPH_YEAST (4-527): 0: 533: 25.61
+	Sc
		579422 GBB_YEAST (2-340): 5.29e-76: 241: 36.01		TCPG_YEAST (2-527): 0: 530: 27.64
+	Hs
		573205 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		TCPA_HUMAN (23-523): 2.19e-67: 228: 28.68
+	Hs
		573204 GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29		TCPA_HUMAN (23-523): 2.19e-67: 228: 28.68
+	Hs
		573346 WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39		TCPA_HUMAN (23-523): 2.19e-67: 228: 28.68
+	Hs
		573384 POC1B_HUMAN (126-340): 2.42e-64: 212: 20.37		TCPA_HUMAN (23-523): 2.19e-67: 228: 28.68