Interactor 1: RL11 (P62913)
Large ribosomal subunit protein uL5 (60S ribosomal protein L11) (CLL-associated antigen KW-12)
Gene: RPL11

Interactor 2: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 1.00 0.995

The method score is based on:

Property Details
Experiments 23507139, 27856536, 29057323, 14612427, 22467867, 29702115, 31903119, 32483207, 32334023, 32516735, 33961781, 35205710, 35073964, 16803902, 15308643, 21804542, 20554519, 18560357, 21903592, 12842086 and 25 others

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Identification Methods affinity chromatography technology, pull down, biochemical, two hybrid, anti bait coimmunoprecipitation, two hybrid array, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ribosomal_L5~zf-RanBP, Ribosomal_L5_C~zf-RanBP
Common GO terms GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008097 - 5S rRNA binding
and 4 others

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Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 178
Hs

1 491
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024