Protein: ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 2) (COBW domain-containing protein 2)

Gene: ZNG1B
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q8IUF1

Gene Ontology (top 5):
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016787 - hydrolase activity
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1307354

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

3

3

High-throughput

0.861

High

1196350

ZNG1F
Zinc-regulated GTPase metalloprotein activator 1F

2

3

High-throughput

0.712

High

212969

HS12A
Heat shock 70 kDa protein 12A

3

2

High-throughput

0.667

High

921383

MAP11
Methionine aminopeptidase 1

3

3

High-throughput

0.667

High

163800

TCRG1
Transcription elongation regulator 1

2

1

High-throughput

0.628

High

909080

NEK4
Serine/threonine-protein kinase Nek4

2

1

High-throughput

0.611

High

1307357

TBB1
Tubulin beta-1 chain

2

2

High-throughput

0.611

High

622465

ELK1
ETS domain-containing protein Elk-1

2

6

High-throughput

0.571

High

1307368

KLK5
Kallikrein-5

2

6

High-throughput

0.549

High

848044

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

1

High-throughput

0.536

High

896409

ERF
ETS domain-containing transcription factor ERF

1

6

High-throughput

0.536

High

981882

RL23
Large ribosomal subunit protein uL14

1

1

High-throughput

0.536

High

1111462

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

2

High-throughput

0.536

High

1113614

CUL3
Cullin-3

1

1

High-throughput

0.536

High

1180065

PWP3A
PWWP domain-containing DNA repair factor 3A

1

1

High-throughput

0.536

High

1307366

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

2

High-throughput

0.536

High

143869

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.513

High

298608

RAD17
Cell cycle checkpoint protein RAD17

1

0

High-throughput

0.513

High

1197525

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.513

High

1230722

Z518A
Zinc finger protein 518A

1

0

High-throughput

0.513

High

1307362

SMYD2
N-lysine methyltransferase SMYD2

1

0

High-throughput

0.513

High

1307363

UFSP2
Ufm1-specific protease 2

1

0

High-throughput

0.513

High

1307369

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

691212

1433T
14-3-3 protein theta

1

0

High-throughput

0.493

High

231052

VEGFD
Vascular endothelial growth factor D

1

3

High-throughput

0.489

High

273772

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

4

High-throughput

0.489

High

634776

GRAH
Granzyme H

1

4

High-throughput

0.489

High

841564

I12R1
Interleukin-12 receptor subunit beta-1

1

1

High-throughput

0.489

High

1248311

SFTA2
Surfactant-associated protein 2

1

1

High-throughput

0.489

High

1307345

F174A
Membrane protein FAM174A

1

2

High-throughput

0.489

High

1307348

UCN3
Urocortin-3

1

1

High-throughput

0.489

High

1307349

SNX21
Sorting nexin-21

1

2

High-throughput

0.489

High

1307356

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

4

High-throughput

0.489

High

1307359

NSUN3
tRNA

1

1

High-throughput

0.489

High

1307360

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

3

High-throughput

0.489

High

1307364

DKKL1
Dickkopf-like protein 1

1

2

High-throughput

0.489

High

1005807

RPP30
Ribonuclease P protein subunit p30

1

1

High-throughput

0.479

High

1254505

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1307350

CI072
Guanine nucleotide exchange factor C9orf72

1

4

High-throughput

0.479

High

1307353

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

1

High-throughput

0.479

High

1307355

EGLN1
Egl nine homolog 1

1

1

High-throughput

0.479

High

1307370

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

1

High-throughput

0.479

High

293966

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

629950

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

930332

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

0

High-throughput

0.458

High

930744

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

0

High-throughput

0.458

High

973063

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.458

High

1117108

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

1144061

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.458

High

1307346

MORC4
MORC family CW-type zinc finger protein 4

1

0

High-throughput

0.458

High

1307365

AGO2
Protein argonaute-2

1

0

High-throughput

0.458

High

564023

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.445

High

1307347

APBB2
Amyloid beta precursor protein binding family B member 2

1

2

High-throughput

0.445

High

630314

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

2

High-throughput

0.437

High

675074

TNR6
Tumor necrosis factor receptor superfamily member 6

1

2

High-throughput

0.437

High

1178235

CL16A
Protein CLEC16A

1

4

High-throughput

0.437

High

1307358

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.437

High

295604

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.426

High

1307361

ELL3
RNA polymerase II elongation factor ELL3

1

0

High-throughput

0.426

High

1307351

OPALI
Opalin

1

1

High-throughput

0.407

High

1307352

Q96T11
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.407

High

717108

ECHM
Enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.282

High

1218152

CAHD1
VWFA and cache domain-containing protein 1

1

0

High-throughput

0.279

Low

1253698

CO039
Uncharacterized protein C15orf39

1

0

High-throughput

0.279

Low

1307343

MICU2
Calcium uptake protein 2, mitochondrial

1

0

High-throughput

0.279

Low

1307344

CBR4
3-oxoacyl-[acyl-carrier-protein] reductase

1

0

High-throughput

0.279

Low

921441

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

139262

UPK2
Uroplakin-2

1

0

High-throughput

0.232

Low

1307367

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025