Interactor 1: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Interactor 2: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 34462738
Identification Methods pull down, mass spectrometry studies of complexes
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pro_isomerase~Pro_isomerase
Common GO terms GO:0000413 - protein peptidyl-prolyl isomerization
GO:0001666 - response to hypoxia
GO:0001933 - negative regulation of protein phosphorylation
GO:0001934 - positive regulation of protein phosphorylation
GO:0003723 - RNA binding
and 43 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 165
Hs

1 165
+ Hs
+ Hs
+ Hs
+ Ce
+ Zm
+ Hs
+ Zm
+ Sc
+ Sc
+ Hs
+ Hs

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Last updated: 15 Jul 2024