HitPredict

Interactor 1: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Interactor 2: IF4A2 (Q14240)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25678563
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 407
+	Hs
		892770 PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00		IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88
+	Hs
		1271695 PPIE_HUMAN (2-163): 2.08e-88: 262: 67.28		DDX17_HUMAN (25-407): 4.76e-131: 395: 31.20
+	Hs
		571634 PPIE_HUMAN (2-163): 2.08e-88: 262: 67.28		DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30
+	Hs
		133966 PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00		DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51
+	Hs
		134252 PPIE_HUMAN (2-163): 2.08e-88: 262: 67.28		DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51
+	Hs
		757552 PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00		IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65
+	Hs
		757802 PPIE_HUMAN (2-163): 2.08e-88: 262: 67.28		IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65