HitPredict

Interactor 1: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Interactor 2: H2AW (Q9P0M6)
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Gene: MACROH2A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 372
+	Hs
		260831 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Rn
		70076 UBC_RAT (1-119): 1.57e-36: 134: 68.29		B1WC28_RAT (1-372): 8.13e-153: 436: 98.39
+	Hs
		555403 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		391643 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		470331 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2A1_HUMAN (1-126): 6.37e-64: 201: 60.47
+	Hs
		924034 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2A2A_HUMAN (1-126): 4.27e-64: 201: 62.02
+	Hs
		924049 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2A3_HUMAN (1-126): 5.3e-64: 201: 61.24
+	Hs
		555404 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		924374 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A1C_HUMAN (1-126): 2.96e-64: 202: 61.24
+	Hs
		924397 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A1J_HUMAN (1-125): 2.23e-64: 202: 60.94
+	Hs
		391644 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		470332 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A1_HUMAN (1-126): 6.37e-64: 201: 60.47
+	Hs
		924322 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A2A_HUMAN (1-126): 4.27e-64: 201: 62.02
+	Hs
		924334 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A3_HUMAN (1-126): 5.3e-64: 201: 61.24
+	Hs
		924387 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A1H_HUMAN (1-125): 5.02e-64: 201: 60.94
+	Rn
		474085 UBC_RAT (1-119): 1.57e-36: 134: 68.29		H2A2A_RAT (1-126): 4.27e-64: 201: 62.02
+	Hs
		474911 UBB_HUMAN (1-76): 6.65e-36: 125: 100.00		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Dm
		950447 R9PY16_DROME (1-68): 7.11e-29: 108: 91.18		H2A_DROME (14-122): 3.54e-63: 199: 67.89
+	Sc
		392251 RL40A_YEAST (1-125): 2.07e-42: 139: 64.00		H2A2_YEAST (14-124): 2.55e-41: 143: 65.77
+	At
		1092092 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		H2A6_ARATH (3-125): 6.02e-40: 139: 63.42