HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 535
+	Hs
		924818 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		826606 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		573207 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821158 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		411833 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		411670 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		411642 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		1046418 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		943224 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		411588 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		411639 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		412325 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		412130 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		826655 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		573257 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821206 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		412086 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		411996 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		412084 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		433248 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		TCPA_HUMAN (5-533): 0: 541: 34.30