HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: PFKAP (Q01813)
ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)
Gene: PFKP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0044877 - protein-containing complex binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 784
+	Hs
		893912 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		900389 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		437736 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		437798 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		437737 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		437732 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		PFKAM_HUMAN (13-779): 0: 1030: 71.78