HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: RAB23 (Q9ULC3)
Ras-related protein Rab-23
Gene: RAB23

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 237
+	Hs
		925294 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RAB35_HUMAN (2-179): 1.06e-94: 277: 35.96
+	Hs
		545392 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		RAB35_HUMAN (2-179): 1.06e-94: 277: 35.96
+	Hs
		1070394 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		RAB35_HUMAN (2-179): 1.06e-94: 277: 35.96
+	Hs
		918847 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RAB1A_HUMAN (2-201): 1.02e-86: 257: 30.35
+	Hs
		564470 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		RAB1A_HUMAN (2-201): 1.02e-86: 257: 30.35
+	Hs
		925600 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RAB1B_HUMAN (2-201): 1.76e-85: 254: 31.34
+	Hs
		894716 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RAB8A_HUMAN (2-200): 9.67e-84: 249: 29.50
+	Hs
		913995 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RB11A_HUMAN (3-210): 2.35e-83: 249: 29.67
+	Hs
		545307 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		RAB1A_HUMAN (2-201): 1.02e-86: 257: 30.35
+	Hs
		564466 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		RAB8A_HUMAN (2-200): 9.67e-84: 249: 29.50
+	Hs
		545692 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		RAB23_HUMAN (1-237): 1.39e-84: 253: 100.00
+	Hs
		918948 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		RAB1A_HUMAN (2-201): 1.02e-86: 257: 30.35
+	Hs
		1330982 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		RAB23_HUMAN (1-237): 1.39e-84: 253: 100.00
+	Hs
		545295 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		RAB8A_HUMAN (2-200): 9.67e-84: 249: 29.50
+	Hs
		545305 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		RB11A_HUMAN (3-210): 2.35e-83: 249: 29.67
+	Hs
		894804 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		RAB8A_HUMAN (2-200): 9.67e-84: 249: 29.50
+	Hs
		844863 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RAB7A_HUMAN (7-172): 2.64e-33: 121: 35.47
+	Hs
		564453 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		RAB7A_HUMAN (7-172): 2.64e-33: 121: 35.47
+	Hs
		545270 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		RAB7A_HUMAN (7-172): 2.64e-33: 121: 35.47
+	Hs
		845248 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		RAB7A_HUMAN (7-172): 2.64e-33: 121: 35.47