HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSMD3 (O43242)
26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58)
Gene: PSMD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 301 Hs			1 534
+	Hs
		198539 PRS6A_HUMAN (20-301): 6.23e-77: 242: 95.47		PSMD3_HUMAN (1-534): 0: 642: 100.00
+	Hs
		198562 PRS7_HUMAN (14-300): 2.33e-68: 220: 31.71		PSMD3_HUMAN (1-534): 0: 642: 100.00
+	Hs
		198568 PRS6B_HUMAN (9-301): 2.8e-68: 220: 34.13		PSMD3_HUMAN (1-534): 0: 642: 100.00
+	Hs
		198596 PRS4_HUMAN (18-301): 6.7e-67: 217: 36.81		PSMD3_HUMAN (1-534): 0: 642: 100.00
+	Dm
		627122 PRS4_DROME (51-301): 1.04e-87: 270: 40.00		PSMD3_DROME (40-533): 0: 562: 57.49
+	Dm
		627128 Q7KMQ0_DROME (14-300): 2.08e-78: 246: 31.36		PSMD3_DROME (40-533): 0: 562: 57.49
+	Hs
		198587 TERA_HUMAN (4-301): 6.57e-45: 164: 23.64		PSMD3_HUMAN (1-534): 0: 642: 100.00
+	Hs
		87545 C9JUP7_HUMAN (49-301): 7.27e-44: 161: 26.87		PSMD3_HUMAN (1-534): 0: 642: 100.00
+	Dm
		627134 Q9V3V6_DROME (34-301): 1.89e-71: 228: 85.82		PSMD3_DROME (40-533): 0: 562: 57.49
+	Dm
		627136 Q9V405_DROME (15-301): 4.18e-69: 222: 33.10		PSMD3_DROME (40-533): 0: 562: 57.49
+	Dm
		186101 PRS8_DROME (54-300): 1.63e-68: 220: 34.68		PSMD3_DROME (40-533): 0: 562: 57.49
+	At
		1339246 PRS4A_ARATH (61-301): 2.11e-49: 171: 39.00		PSD3B_ARATH (33-533): 0: 575: 42.66
+	At
		1338931 PRS4A_ARATH (61-301): 2.11e-49: 171: 39.00		PSD3A_ARATH (33-533): 0: 574: 43.96
+	Sc
		703801 PRS6B_YEAST (13-301): 5.65e-71: 227: 32.19		RPN3_YEAST (45-531): 1.11e-166: 484: 30.87
+	Sc
		703632 PRS6A_YEAST (24-301): 1.52e-69: 223: 65.85		RPN3_YEAST (45-531): 1.11e-166: 484: 30.87
+	Sc
		766858 PRS4_YEAST (129-301): 4.7e-51: 175: 50.29		RPN3_YEAST (45-531): 1.11e-166: 484: 30.87
+	Hs
		875434 TERA_HUMAN (4-301): 6.57e-45: 164: 23.64		CSN3_HUMAN (226-511): 1.4e-95: 298: 20.54