HitPredict

Interactor 1: VAMP2 (P63044)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Interactor 2: SYPH (Q62277)
Synaptophysin (BM89 antigen) (Major synaptic vesicle protein p38)
Gene: Syp

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

The method score is based on:

Property	Details
Experiments	20114047, 21645620, 18706977, 19022416
Identification Methods	affinity chromatography technology, fluorescent resonance energy transfer, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000149 - SNARE binding GO:0008021 - synaptic vesicle GO:0016020 - membrane GO:0017075 - syntaxin-1 binding GO:0030672 - synaptic vesicle membrane and 6 others more... GO:0044306 - neuron projection terminus GO:0044877 - protein-containing complex binding GO:0045202 - synapse GO:0048471 - perinuclear region of cytoplasm GO:0048488 - synaptic vesicle endocytosis GO:0060203 - clathrin-sculpted glutamate transport vesicle membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	116
Mm

1	314

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024