HitPredict

Interactor 1: GNAS2 (P63092)
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)
Gene: GNAS

Interactor 2: SNX13 (Q9Y5W8)
Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)
Gene: SNX13

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	11729322
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	G-alpha~RGS
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 394 Hs			1 968
+	Hs
		170629 GNAS2_HUMAN (1-394): 1.94e-179: 506: 100.00		AXIN1_HUMAN (291-583): 2.81e-41: 165: 14.24
+	Hs
		782024 GNAS2_HUMAN (1-394): 1.94e-179: 506: 100.00		RGS2_HUMAN (323-522): 1.35e-34: 133: 15.84
+	Hs
		207505 GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83		RGS14_HUMAN (311-587): 2.82e-41: 162: 14.34
+	Hs
		207517 GNAI1_HUMAN (1-394): 5.37e-158: 450: 39.09		RGS14_HUMAN (311-587): 2.82e-41: 162: 14.34
+	Hs
		207507 GNAI3_HUMAN (1-394): 1.06e-155: 444: 38.58		RGS14_HUMAN (311-587): 2.82e-41: 162: 14.34
+	Hs
		391357 GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83		RGS3_HUMAN (327-520): 7.7e-37: 152: 18.88
+	Hs
		391473 GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83		RGS18_HUMAN (321-544): 7.74e-40: 149: 15.93
+	Rn
		500350 GNAI1_RAT (1-394): 2.53e-158: 451: 39.34		RGS4_RAT (324-537): 3.19e-40: 149: 16.13
+	Hs
		926720 GNAI1_HUMAN (1-394): 5.37e-158: 450: 39.09		RGS18_HUMAN (321-544): 7.74e-40: 149: 15.93
+	Hs
		391358 GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83		RGS4_HUMAN (324-537): 1.12e-39: 147: 16.13
+	Hs
		834937 GNAI1_HUMAN (1-394): 5.37e-158: 450: 39.09		RGS4_HUMAN (324-537): 1.12e-39: 147: 16.13
+	Hs
		444692 GNAI3_HUMAN (1-394): 1.06e-155: 444: 38.58		RGS3_HUMAN (327-520): 7.7e-37: 152: 18.88
+	Hs
		444680 GNAI3_HUMAN (1-394): 1.06e-155: 444: 38.58		RGS2_HUMAN (323-522): 1.35e-34: 133: 15.84
+	Hs
		283156 GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83		RGS20_HUMAN (373-517): 2.02e-12: 71.9: 23.45
+	Hs
		158597 GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83		RGS12_HUMAN (372-559): 1.06e-11: 71.5: 23.04
+	Hs
		283183 GNAI1_HUMAN (1-394): 5.37e-158: 450: 39.09		RGS20_HUMAN (373-517): 2.02e-12: 71.9: 23.45
+	Hs
		158608 GNAI1_HUMAN (1-394): 5.37e-158: 450: 39.09		RGS12_HUMAN (372-559): 1.06e-11: 71.5: 23.04
+	Hs
		158599 GNAI3_HUMAN (1-394): 1.06e-155: 444: 38.58		RGS12_HUMAN (372-559): 1.06e-11: 71.5: 23.04
+	Hs
		210414 GNAI1_HUMAN (1-394): 5.37e-158: 450: 39.09		RGS10_HUMAN (373-521): 2.48e-11: 65.4: 19.46
+	Hs
		210409 GNAI3_HUMAN (1-394): 1.06e-155: 444: 38.58		RGS10_HUMAN (373-521): 2.48e-11: 65.4: 19.46