HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019901 - protein kinase binding GO:0044877 - protein-containing complex binding GO:0098978 - glutamatergic synapse
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Mm			1 724
+	Mm
		910260 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Mm
		1143489 1433B_MOUSE (1-242): 1.98e-128: 364: 86.78		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Mm
		905344 1433G_MOUSE (1-240): 8.4e-109: 315: 74.59		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Dm
		664599 1433Z_DROME (1-245): 3.35e-143: 402: 81.63		DLG1_DROME (22-322): 5.59e-26: 116: 20.79
+	Dm
		677686 1433E_DROME (2-242): 3.33e-143: 402: 66.67		DLG1_DROME (22-322): 5.59e-26: 116: 20.79
+	Hs
		927034 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		646881 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		683339 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		159186 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		CSKP_HUMAN (6-381): 1.53e-20: 99: 14.43
+	Hs
		927332 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Hs
		909845 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Hs
		647130 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Hs
		683563 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Hs
		904552 1433G_HUMAN (1-240): 8.4e-109: 315: 74.59		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		982003 1433F_HUMAN (2-240): 5.21e-108: 313: 74.49		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		684030 1433S_HUMAN (1-237): 2.52e-103: 301: 71.55		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		904899 1433G_HUMAN (1-240): 8.4e-109: 315: 74.59		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Hs
		982311 1433F_HUMAN (2-240): 5.21e-108: 313: 74.49		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55