HitPredict

Interactor 1: 1433Z (P63102)
14-3-3 protein zeta/delta (Mitochondrial import stimulation factor S1 subunit) (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: Ywhaz

Interactor 2: RIMS1 (Q9JIR4)
Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1)
Gene: RIMS1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	18799741
Identification Methods	pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding GO:0044325 - transmembrane transporter binding GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Rn			1 1615
+	Rn
		910361 1433E_RAT (2-241): 9.9e-144: 403: 68.18		RIMS1_RAT (1-1615): 0: 922: 100.00
+	Hs
		135776 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		P3C2B_HUMAN (689-889): 8.18e-42: 171: 24.51
+	Hs
		135774 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		P3C2B_HUMAN (689-889): 8.18e-42: 171: 24.51
+	Rn
		910358 1433E_RAT (2-241): 9.9e-144: 403: 68.18		NEDD4_RAT (1472-1612): 3.71e-29: 128: 20.00
+	Hs
		927423 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		NED4L_HUMAN (1459-1575): 8.58e-25: 114: 23.77
+	Hs
		909930 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		NED4L_HUMAN (1459-1575): 8.58e-25: 114: 23.77
+	Mm
		910302 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		NED4L_MOUSE (1472-1575): 4.2e-24: 112: 24.53
+	Mm
		808343 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		NEDD4_MOUSE (1471-1610): 3.16e-22: 106: 20.83
+	Hs
		927470 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ESYT1_HUMAN (1157-1602): 9.33e-16: 85.4: 12.83
+	Hs
		909970 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ESYT1_HUMAN (1157-1602): 9.33e-16: 85.4: 12.83
+	Hs
		927239 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		RIMS1_HUMAN (174-883): 8.12e-14: 79.3: 13.88
+	Mm
		926829 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		RIMS3_MOUSE (635-900): 7.69e-14: 76.5: 17.69
+	Hs
		397155 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KPCG_HUMAN (1463-1582): 2.58e-14: 80.4: 33.87
+	Hs
		909754 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RIMS1_HUMAN (174-883): 8.12e-14: 79.3: 13.88
+	Hs
		566348 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		KPCA_HUMAN (1463-1582): 1.63e-12: 74.6: 31.15
+	Mm
		910341 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		RIMS2_MOUSE (299-883): 5.2e-13: 76.6: 12.90
+	Mm
		910280 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		RIMS3_MOUSE (635-900): 7.69e-14: 76.5: 17.69
+	Hs
		128838 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		P3C2A_HUMAN (757-881): 4.06e-10: 67: 35.94
+	Hs
		128836 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		P3C2A_HUMAN (757-881): 4.06e-10: 67: 35.94
+	Hs
		128810 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		P3C2A_HUMAN (757-881): 4.06e-10: 67: 35.94