HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: DSC1 (Q08554)
Desmocollin-1 (Cadherin family member 1) (Desmosomal glycoprotein 2/3) (DG2/DG3)
Gene: DSC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34825085
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 894
+	Hs
		926944 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DSC2_HUMAN (29-894): 0: 760: 53.66
+	Hs
		909460 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DSC2_HUMAN (29-894): 0: 760: 53.66
+	Hs
		646814 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		DSC2_HUMAN (29-894): 0: 760: 53.66
+	Hs
		683279 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		DSC2_HUMAN (29-894): 0: 760: 53.66
+	Hs
		521850 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		CADH1_HUMAN (23-890): 0: 699: 29.13
+	Hs
		521844 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		CADH1_HUMAN (23-890): 0: 699: 29.13
+	Hs
		521751 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		CADH1_HUMAN (23-890): 0: 699: 29.13
+	Hs
		904459 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		DSC2_HUMAN (29-894): 0: 760: 53.66
+	Hs
		971008 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		DSC2_HUMAN (29-894): 0: 760: 53.66
+	Hs
		683976 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		DSC2_HUMAN (29-894): 0: 760: 53.66
+	Hs
		521752 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		CADH1_HUMAN (23-890): 0: 699: 29.13
+	Hs
		927041 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DSC3_HUMAN (1-331): 4.44e-27: 120: 12.75
+	Hs
		927030 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DSG2_HUMAN (31-390): 4.92e-21: 101: 17.41
+	Hs
		646879 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		DSG2_HUMAN (31-390): 4.92e-21: 101: 17.41
+	Hs
		683336 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		DSG2_HUMAN (31-390): 4.92e-21: 101: 17.41
+	Hs
		904547 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		DSG2_HUMAN (31-390): 4.92e-21: 101: 17.41
+	Hs
		981999 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		DSG2_HUMAN (31-390): 4.92e-21: 101: 17.41
+	Hs
		684028 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		DSG2_HUMAN (31-390): 4.92e-21: 101: 17.41